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FDA approved since 2003

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FDA Approved ED medication

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Better Knowledge, Better Health

Learn about Tadalafil (Generic Cialis)

Whether you need a quick performance boost or a daily dose of confidence, tadalafil is the drug for you. This FDA-approved med is the generic version of Cialis, offering the same benefits at a lower cost.

Tadalafil can be taken as a low dose, once-daily solution, or as a higher as-needed dose 30 minutes before sex. Either way, tadalafil's remarkable 36-hour duration and minimal side effects have earned it the “weekend pill” moniker.

Tadalafil works by improving how your body responds to sexual arousal. You see, intimacy naturally triggers a chain reaction that first fills the penis with blood for an erection. Then, the body releases PDE5 to stop an erection when sex is over. Tadalafil works on both these stages to help you achieve and maintain an erection.

More specifically, tadalafil relaxes the penile blood vessels and sends stronger blood flow to your member for a strong erection. At the same time, it prevents PDE5 from stopping the erection, helping you maintain your hardness for a satisfying experience. 

Tadalafil on-demand boasts an impressive 36-hour window. This allows ample time for spontaneous sex, adding flexibility to your intimate moments.

If you want even more spontaneity, tadalafil daily allows you to plan less and enjoy more. It’s taken once daily, and you can enjoy sex anytime. 

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How to get Tadalafil from Mail My Meds

Avoid the appointments, waiting rooms and awkwardness and get treat online. Here is what to expect.


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Affordable 2-day shipping (discretely packaged)

Affordable 2-day shipping (discretely packaged)


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The Mail My Meds' way

  • Tell us about your medical history, answer a questionnaire specific to your ED symptoms, and confirm your identity. During this process, we also ask you about your treatment preferences.
  • A medical licensed professional will review your medical history, preferences and determine your treatment plan. This typically occurs within 24 hours of you completing step 1. Our medical team may reach out to you if they have any questions.
  • Your treatment ships out in 1-2 days from our partnering pharmacy, directly to your door. Delivery is typically 1 -3 days.
  • Receive and begin your treatment.
  • Receive refills based on your schedule!
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The old way

  • Find a doctor who accepts your insurance
  • Make an appointment with the doctor
  • Travel to the doctor’s office
  • Sit in the waiting room until the doctor is ready for you
  • Consult with the doctor to get your prescription
  • Drive to the pharmacy to pick up your prescription
Better Knowledge, Better Health

Common questions about Tadalafil (Generic Cialis)

This depends entirely on you and your needs. If you want a spontaneous solution, as-needed tadalafil can be taken 30 minutes before sex. Once in your system, you can relax and enjoy yourself for 36 hours.

If you want to skip the planning altogether, tadalafil daily is a great choice. It’s taken once daily so it’s always in your body, and you can have sex anytime.

Tadalafil is the generic version of Cialis. The strength, the way they work, and the effectiveness of both medications are the same.

The key difference is the cost. Tadalafil offers the same benefits as Cialis at a much lower price.

Although tadalafil and Viagra are both effective ED meds, they use different ingredients. While some men swear by the original blue pill containing sildenafil, others choose tadalafil for its flexibility and long-lasting benefits.

Tadalafil offers daily and on-demand options to suit your lifestyle. If you have a lot of sex, going the daily route is great because then you don't have to plan each time. If you're a once-in-a-while type of guy, a simple dose before sex will likely meet your needs.

Having one glass shouldn’t cause any issues while taking tadalafil.

But, if you drink too much, you may experience low blood pressure, leading to unwanted (and potentially dangerous) symptoms such as headache, dizziness, and fainting.

If you choose to drink, please do so in limited quantities and monitor your symptoms.

Tadalafil can be taken with or without food. Either way, the effectiveness of tadalafil stays the same.

This depends on whether you take tadalafil daily or on-demand.

If you prefer the convenience of tadalafil on-demand, you'll take either 10 mg or 20 mg about half an hour before having sex.

If you choose daily tadalafil, you'll most likely start out with 5 mg. Daily tadalafil is always in your system, so there's no need for higher doses!

In both situations, do not exceed 20 mg per day. It may be tempting but overdosing on tadalafil doesn't improve performance and can instead lead to long and painful erections.

Common side effects of tadalafil include headache, indigestion, back pain, muscle pain, stuffy nose, and flushing.

These symptoms usually occur within 48 hours and disappear as the drug wears off. If you continue to experience side effects after a week, it's important to talk to your doctor. If any serious side effects occur, such as dizziness from low blood pressure or a prolonged erection, we advise you to seek emergency medical attention.

Yes! In fact, a study posted in the Journal of European Urology found no issues associated with long-term tadalafil usage.1

But, like any drug, it’s crucial to monitor your symptoms and let your doctor know if you notice anything concerning.

Offered Treatments

Explore other ED Treatments

Mail My Meds offers other treatments for ED other than Tadalafil.